Mastering the Basics of Clinical Centrifuge Use and Maintenance: A Comprehensive Guide

Clinical centrifuges are an essential piece of equipment in any medical laboratory. They spin liquid samples at high speeds, allowing the samples to be separated into their individual components. Knowing how to properly use and maintain a clinical centrifuge is crucial for getting accurate results.

In this post, we’ll go over the basics of clinical centrifuge use and maintenance so you can get the most out of your equipment.

Types of Clinical Centrifuges

Before we dive into the specifics of using and maintaining a clinical centrifuge, you should first understand that there are different types of centrifuges available. Each type serves a specific purpose and has its own set of advantages and disadvantages. Here are the most common types:

  • Microcentrifuges – These are small, but high-speed centrifuges used for separating components from very small sample sizes (usually 2 mL or less). Microcentrifuges are often used for DNA extraction or protein purification workflows. They can easily spin samples up to 18,000 RPM.
  • Clinical Centrifuges – clinical centrifuges generally used for blood and urine samples. They can handle larger sample sizes (up to 10 mL) and usually spin at around 4,000 RPM. These machines are ideal for applications requiring separation within minutes.
  • Ultracentrifuges – Ultracentrifuges are designed for even higher speeds (up to 100,000 RPM) and have a much larger capacity than other types (up to 200 mL). These machines are usually used for separating large particles such as cells or organelles from body fluids like blood or urine.

How To Use A Clinical Centrifuge Safely

Using a clinical centrifuge safely is essential if you want accurate results without any risk of injury or contamination. Here’s what you need to do before operating your machine:

  • Check all connections between the rotor head and motor drive unit to make sure they’re secure.
  • Check the rotor head balance by placing it on top of a flat surface; it should remain stationary without any wobbling motion.
  • Make sure all safety locks are engaged prior to starting your machine.
  • Check that all sample chambers in the rotor head have been securely sealed with caps. This will prevent any spills during operation.
  • Check that no foreign objects have gotten into the rotor head chamber during loading or unloading. These could cause damage or injury if left unchecked.
  • Check that any samples being loaded have been placed in an appropriate container with a secure lid. This will ensure that no sample material gets spilled during operation.
  • Make sure all personnel working near the machine are wearing protective clothing such as goggles and gloves; this will protect them from potential hazards associated with spinning liquids at high speeds.

How To Maintain A Clinical Centrifuge Properly 

Just like any other piece of lab equipment, regular maintenance is essential for clinical centrifuges to last longer and perform better over time. Here’s what you should do on a regular basis:

  • Clean all external surfaces regularly with an appropriate cleaner. This will prevent dirt build-up which can interfere with proper performance over time.
  • Visually inspect all parts regularly for signs of wear or damage. Replace any parts as needed so that your machine remains in good working order at all times.
  • Calibrate your machine regularly according to the manufacturer’s instructions. This will ensure that it remains accurate throughout its lifetime.
  • Follow manufacturer’s instructions when lubricating moving parts. Improper lubrication can cause damage which may lead to costly repairs down the line.


Using a clinical centrifuge correctly is key if you want consistent results from your experiments every time—but it doesn’t end there!

Staying on top of regular maintenance is just as important if you want your machine running optimally for years to come. By following these basic tips for safe use and proper maintenance, you’ll be able to get reliable results from your clinical centrifuge each time it’s put into use!